Solid tumors in childhood: risk-based management

Proton Radiotherapy for Solid Tumors of Childhood

The increasing efficacy of pediatric cancer therapy over the past four decades has produced many long-term survivors that now struggle with serious treatment related morbidities affecting their quality of life. Radiation therapy is responsible for a significant proportion of these late effects, but a relatively new and emerging modality, proton radiotherapy hold great promise to drastically red...

Serum microRNAs in childhood tumors 1 Solid tumors of childhood display specific serum microRNA profiles

1 Solid tumors of childhood display specific serum microRNA profiles Matthew J. Murray, Katie L. Raby, Harpreet K. Saini, Shivani Bailey, Sophie V. Wool, Jane M. Tunnacliffe, Anton J. Enright, James C. Nicholson, Nicholas Coleman. 1 Department of Paediatric Haematology and Oncology, Addenbrooke’s Hospital, Hills Road, Cambridge, CB2 0QQ, UK 2 Department of Pathology, University of Cambridge, Te...

Management of Leptomeningeal Disease From Solid Tumors.

Leptomeningeal carcinomatosis, known by a variety of names, including leptomeningeal metastases and neoplastic meningitis, indicates spread of tumor to the cerebrospinal fluid (CSF) and invasion of the subarachnoid space. The term leptomeningeal (from the Greek lepto, meaning “fine” or “slight”) describes the thin meninges, the arachnoid and the pia mater, between which the CSF is located. Alth...

Hematopoietic Cell Transplantation for Solid Tumors of Childhood

Solid Malignant Tumors of Infancy and Childhood: A Histopathological Study

In general, the features of malignancies in children differ biologically and histologically from those of adults with respect to incidence, type of tumor, underlying familial or genetic aberration and Tendency to regress spontaneously or cytodifferantiate. In recent years, identification of specific genes, oncogenes, tumor markers and other biological and pathological factors have played an imp...